Not far from the Church of the Palomba, the chapel of the Holy Spirit is carved along the walls of a narrow path.
The interior is at a lower level than the entrance floor. Along the walls of the only room with a square plan, side stone benches develop, an altar leaning against the back wall with a frescoed palliotto, two small niches on the sides of the arch above the altar. On both side walls residues of frescoes testify that once it had to be completely frescoed.